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Carboxymethyl beta cartodextrin

Carboxymethyl beta cyclodextrin sodium salt

CAS: 218269-34-2

Molecular Formula: C56H84O49

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Carboxymethyl beta cartodextrin - Names and Identifiers

Name Carboxymethyl beta cyclodextrin sodium salt
Synonyms CM- β-CD
Carboxymethyl-β-cyclodextri
Carboxymethyl beta cartodextrin
CARBOXYMETHYL BETA-CYCLODEXTRIN
carboxymethylated-β-cyclodextrin
Carboxymethyl-β-cyclodextrin sodium salt
Carboxymethyl beta cyclodextrin sodium salt
Carboxymethyl-beta-Cyclodextrin sodium salt
β-Cyclodextrin, 3A,3B,3C,3D,6E,6F,6G-heptakis-O-(carboxymethyl)-
CAS 218269-34-2

Carboxymethyl beta cartodextrin - Physico-chemical Properties

Molecular FormulaC56H84O49
Molar Mass1541.24
Density1.82±0.1 g/cm3(Predicted)
Melting Point~245°C (dec.)
Boling Point1774.6±65.0 °C(Predicted)
Solubility H2O: 50mg/mL, clear, colorless
AppearanceWhite powder
pKa3.28±0.10(Predicted)
Storage ConditionSealed in dry,Room Temperature

Carboxymethyl beta cartodextrin - Risk and Safety

WGK Germany3
FLUKA BRAND F CODES3

Carboxymethyl beta cartodextrin - Reference

Reference
Show more
1. Sun, Xiaodong, et al. "Metal organic framework HKUST-1 modified with carboxymethyl-β-cyclodextrin for use in improved open tubular capillary electrochromatographic enantioseparation of five basic drugs." Microchimica Acta 186.7 (2019): 1-8.
2. [IF=4.142] Wu Jia et al."Enantioseparation of chiral β-blockers using polynorepinephrine-coated nanoparticles and chiral capillary electrophoresis."Anal Bioanal Chem. 2019 Apr;411(10):2121-2129
3. [IF=6.529] Yu Yang et al."Long-term treatment of polysaccharides-based hydrogel microparticles as oral insulin delivery in streptozotocin-induced type 2 diabetic mice."Biomed Pharmacother. 2021 Jan;133:110941
4. [IF=5.833] Sun Xiaodong et al."Gold nanoparticles coated with a tetramethylammonium lactobionate ionic liquid for enhanced chiral differentiation in open tubular capillary electrochromatography: application to enantioseparation of β-blockers."Microchim Acta. 2020 M
5. [IF=5.833] Sun Xiaodong et al."Metal organic framework HKUST-1 modified with carboxymethyl-β-cyclodextrin for use in improved open tubular capillary electrochromatographic enantioseparation of five basic drugs."Microchim Acta. 2019 Jul;186(7):1-8
6. [IF=3.935] Xinqi Zhu et al."Synthesis and application of tetramethylammonium-carboxymethylated-β-cyclodextrin: A novel ionic liquid in capillary electrophoresis enantioseparation."J Pharmaceut Biomed. 2020 Feb;180:113030
7. [IF=2.437] Zhifeng Huang et al."A rapid enantioseparation system of capillary electrochromatography modified by electrostatic adsorption with transfersomes."Chirality. 2020 Jan;32(1):98-106
8. [IF=1.618] Zhao Shiyuan et al."Polydopamine Coating Doped with Graphene Oxide Enhances Enantioseparation of Capillary Column."J Chromatogr Sci. 2022 Apr;:

Carboxymethyl beta cartodextrin - Introduction

The Carboxymethyl beta cyclodextrin sodium salt(Carboxymethyl beta cyclodextrin sodium salt) is a compound that is a derivative of cyclodextrins. The following is a description of its nature, use, preparation and safety information:

Nature:
Carboxymethyl beta cyclodextrin sodium salt is a white to off-white powder, which is the sodium salt of carboxymethylated β-cyclodextrin. It has good solubility and can form a solution in water. It can also be stable under acidic conditions.

Use:
Carboxymethyl beta cyclodextrin sodium salt has a wide range of applications in the fields of medicine, food, cosmetics and environment. It can be used as a drug carrier to increase the solubility, stability and bioavailability of drugs. It can also be used as an additive in food, with preservation, stability, aroma and other effects. In addition, it can also be used in cosmetics to enhance the stability and penetration of active ingredients. In the environmental field, it can be used in solid phase extraction, water treatment and so on.

Preparation Method:
The preparation of the Carboxymethyl beta cyclodextrin sodium salt usually uses a carboxymethylation reaction. First, β-cyclodextrin is reacted with chloroacetic acid to form carboxymethylated cyclodextrin, and then with sodium hydroxide to form the sodium salt of the Carboxymethyl beta cyclodextrin sodium salt.

Safety Information:
The Carboxymethyl beta cyclodextrin sodium salt is relatively safe under normal conditions of use. However, in the process of use, still need to pay attention to the following matters:
-Avoid direct contact with skin and eyes. In case of contact, rinse with plenty of water and seek medical advice.
-Avoid inhaling dust and try to operate in a well-ventilated place.
-avoid oral, if taken by mistake, please seek medical attention.
-Avoid direct sunlight and humidity during storage.
-Read the product description carefully before use and follow the relevant safety procedures.

Generally speaking, the Carboxymethyl beta cyclodextrin sodium salt is a multifunctional compound with a wide range of uses. However, in the process of use, it is still necessary to pay attention to safe operation and protection measures. It is recommended to use the Carboxymethyl beta cyclodextrin sodium salt under suitable conditions according to the specific situation.
Last Update:2024-04-09 21:01:54
Carboxymethyl beta cartodextrin
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Carboxymethyl beta cartodextrin
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